- Previous studies suggest that depressed patients who receive treatment with two antidepressant medications at the same time feel better faster than depressed patients who receive treatment with one antidepressant. Studies have also shown that parental remission from depression has a positive effect on children. The current studies compare the ratio and magnitude of a depressed patient's improvement on two versus one standard antidepressant and the effect of this improvement on the children of depressed parents.
Who can participate in the treatment study?
Men and women ages 18-65
Currently depressed English and Spanish speakers
Physically healthy
We cannot include people with bipolar disorder, psychosis, anorexia or bulimia, seizures, pregnant or breastfeeding women, and those with an intolerance for Lexapro or Wellbutrin.
If you volunteer for the treatment study:
You will be evaluated by an experienced psychiatrist.
You will complete various laboratory tests (blood and urine sample, EKG)
If eligible, you will receive free treatment for your depression.
You will meet regularly with a psychiatrist to talk about your symptoms and complete questionnaires.
Who can participate in the child study?
Children ages 7-17 and their parents
Children living at least 50% of the time with the treated parent.
If you volunteer for the child study:
Parents will be asked about their children's symptoms.
Your child will be assessed by a clinically trained researcher.
Children do not receive treatment.
A referral will be provided for your child if needed.
Parents receive $50 per interview and children receive $20-40 per interview.
CONFIDENTIALITY IS PROTECTED
Benefits of participating in our research studies:
Benefits of participating in our research studies:
Receive free treatment for depression by nationally recignized experts if eligible.
Help us develop more effective treatments for depression.
Frinding successful treatment for parents may lead to better help for children.
Contact Monica Alvarez at 212-543-6659 or Mariely Hernandez at 212-543-4314 for more information on the child study.
NYSPI-IRB - Ok for recruitment
10/9/08-10/10/09
IRB# 5588
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